師資

個人簡介:
安俊卿,南方科技大學醫學院研究助理教授,2023年獲得美國佐治亞州立大學博士學位,2023-2025年于南方科技大學醫學院從事博士后研究工作。主要研究方向為心血管疾病的免疫和代謝調控機制。研究工作發表于Cellular&molecular Immunology, Theranostics, Plos Pathogens和 iScience等國際學術期刊。主持國家自然科學基金青年科學基金項目、中國博士后科學基金特別資助(站前)、和中國博士后科學基金面上項目。獲批國家資助博士后計劃C檔。
教育背景:
2017.08-2023.01 佐治亞州立大學,分子與轉化醫學中心,生物醫學科學,博士
2015.09-2017.07 中國農業大學,動物醫學院,基礎獸醫學,碩士
2010.09-2015.07 西北農林科技大學,動物醫學院,動物醫學,學士
工作經歷:
2023.03-2025.02 南方科技大學,醫學院,博士后
2025.03-2025.07 南方科技大學,醫學院,高級研究學者
2025.07-今 南方科技大學,醫學院,研究助理教授
研究領域:
1)動脈粥樣硬化的炎癥調控機制研究
2)病理性心肌重構的代謝調控機制研究
發表論文:
1) An J#, Ouyang L#, Yu C, Carr SM, Ramprasath T, Liu Z, Song P, Zou MH, DingY. Nicotine exacerbates atherosclerosis and plaque instability via NLRP3 inflammasome activation in vascular smooth muscle cells. Theranostics. 2023 May
2) An J, DingY, Yu C, Li J, You S, Liu Z, Song P*, Zou MH*. AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells. iScience. 2021 Dec
3) An J, Zhao X, Wang Y, Noriega J, Gewirtz AT*, Zou J*. Western-style diet impedes colonization and clearance of Citrobacter rodentium. PLoS Pathog. 2021 Apr
4) Zhu H#, Liu Z#*, An J#, Zhang M, Qiu Y, Zou MH. Activation of AMPKα1 is essential for regulatory T cell function and autoimmune liver disease prevention. Cell Mol Immunol.2021.Dec (co-first author)
5) Li J, Yao H, Zhao F, An J, Wang Q, Mu J, Liu Z, Zou MH, Xie Z. Pycard deficiency inhibits microRNA maturation and prevents neointima formation by promoting chaperone-mediated autophagic degradation of AGO2/argonaute 2 in adipose tissue. Autophagy. 2024 Mar.
6) Cai Z, You S, Liu Z, Song P, Zhao F, An J, DingY, He B, Zou MH. Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo. Cell Death Dis. 2024 Mar 14
7) Song P*, An J, Zou MH. Immune Clearance of Senescent Cells to Combat Ageing and Chronic Diseases. Cells. 2020 Mar 10;9(3):671.
8) DingY, Han Y, Lu Q, An J, Zhu H, Xie Z, Song P, Zou MH. Peroxynitrite-Mediated SIRT (Sirtuin)-1 Inactivation Contributes to Nicotine-Induced Arterial Stiffness in Mice. Arterioscler Thromb Vasc Biol.
9) Han C, Yang J, Zhang E, Jiang Y, Qiao A, Du Y, Zhang Q, An J, Sun J, Wang M, Nguyen T, Lal H, Krishnamurthy P, Zhang J, Qin G. Metabolic labeling of cardiomyocyte-derived small extracellular-vesicle (sEV) miRNAs identifies miR-208a in cardiac regulation of lung gene expression. J Extracell Vesicles. 2022 Oct;11(10):e12246.
10) Tian J, Shi R, Xiao P, Liu T, She R, Wu Q, An J, Hao W, Soomro M. Hepatitis E Virus Induces Brain Injury Probably Associated With Mitochondrial Apoptosis. Front Cell Infect Microbiol. 2019 Dec 20; 9:433.
11)Tian J, Shi R, Liu T, She R, Wu Q, An J, Hao W, Soomro MH. Brain Infection by Hepatitis E Virus Probably via Damage of the Blood-Brain Barrier Due to Alterations of Tight Junction Proteins.Front Cell Infect Microbiol. 2019 Mar 19; 9:52.
12) Wu Q, An J, She R, Shi R, Hao W, Soomro M, Yuan X, Yang J, Wang J. Detection of Genotype 4 Swine Hepatitis E Virus in Systemic Tissues in Cross-Species Infected Rabbits. PLoS One. 2017 Jan 27;12(1):e0171277.
13) An J, Liu T, She R, Wu Q, Tian J, Shi R, Hao W, Ren X, Yang Y, Lu Y, Yang Y, Wu Y. Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4. Oncotarget. 2017 Dec 17;9(4):4475-4484.
14) Tang J, Wu Q, Tang X, Shi R, Suo J, Huang G, An J, Wang J, Yang J, Hao W, She R, Suo X. Development of a vivo rabbit ligated intestinal Loop Model for HCMV infection. J Anim Sci Biotechnol. 2016 Dec 13; 7:69.
15)Zhang L, Lu Y, An J, Wu Y, Liu Z, Zou MH. AMPKα2 regulates fasting-induced hyperketonemia by suppressing SCOT ubiquitination and degradation. Sci Rep. 2024 Jan 19;14(1):1713.